We keep on returning to the discussion of CBG benefits and your body. Here’s why:
CBG is a powerful supplement that provides impressive medicinal benefits. The research continues to support CBG, paving its way to become the next natural health phenomenon!
Our classic CBD has a long list of beautiful properties. It will help you focus, remain active, and smile a little wider each day! But CBG has a few talents that CBD can’t compare with. For example, CBG is a more powerful COX1/2 inhibitor than both CBD and THC. COX1/2 is an enzyme that causes both inflammation and pain, making CBG a considerable contender for pain management and recovery.
The Chemical Details
We know why you are here. You were probably wondering if C21H32O2 was the original chemical molecular formula for CBG, cannabigerol. You needed to know that CBG has a molecular weight of 316,48 g/mol. Right?
Okay, maybe not. But, while these details may not help alleviate the symptoms you deal with on a daily basis, we can use science to build confidence in and understand the way our products work. For example, we can use the boiling point of CBG to give our vaping customers a quick tip. The boiling point of CBG is on the higher end when compared with other cannabinoids. You can expect to begin inhaling the CBG cannabinoid, and other heat-resistant cannabinoids like CBC when vaping your flower or appropriate extract at 220°C.
CBG Subjective Effects
When you isolate CBG by vaporizing appropriate products at the right temperature or by taking a CBG oil, you will notice the signature effects of this cannabinoid. From subjective reports, and from what we know about its impacts on the body and mind, CBG can be seen as a mild relaxant. The kind of relaxant that would not space you out, but will help you rest, calm the mind, ease tension in the body, and help you to focus on the present moment. We can quickly see how these subjective experiences are created when looking at the CBG medical benefits. When experiencing the pain reducing, mood elevating, and anti-inflammatory effects of cannabigerol, it is no surprise that we feel present and whole.
CBG interacts with a large number of factors in the body. Most notably, CBG works within the endocannabinoid system (ECS). As the name suggests, this cannabinoid network reacts positively to hemp and cannabis compounds like CBD, CBG, and THC, etc. This network uses two primary cannabinoid receptors that can appear in nearly every tissue of the human body. These cannabinoid receptors are known as CB1 and CB2.
CBG Endocannabinoid Receptor Activity:
CB1 Receptor: Mild Antagonist (inhibits activity at this receptor)
CB2 Receptor: Agonist (activates this receptor)
The healthy activity of the ECS relies on a balanced activation of CB1 and CB2. Each cannabinoid uniquely relates to these receptors, creating a specific therapeutic action. CB1 and CB2 often create opposing effects on a system of the body, allowing their respective activation or inhibition to develop a state of homeostasis. In this case, CBG reduces the activity of CB1 receptors and increases the activity of CB2 receptors.
Balanced CB1 activity can be connected to mood, neuroprotection, digestive health, anti-inflammation, pain-regulation and more. CB2 activity carries similar qualities helping to create anti-nausea, neuroprotective, anti-inflammatory, and mood elevating effects.
Additional CBG Receptor Activity + Enzyme Inhibition:
5HT1a Receptor: Antagonist
Alpha-2 Adrenergic Receptor: Agonist
COX1/2 Enzyme: Inhibitor
CBG also limits the activity of 5HT1a receptors and boosts the activity of alpha-2 adrenergic receptors. Meanwhile, it is directly targeting and reducing levels of the inflammatory and pain causing COX1 and COX2 enzymes.
5HT1a serotonin receptor antagonism has been connected to increased memory and learning, supporting CBGs neuroprotective benefits. Alpha-2 adrenergic receptor activity can reduce pain, mood disorders, and addictive tendencies. COX1 and COX2 enzymes have pain-inducing, inflammatory, and neurotoxic effects. CBG’s inhibition of these two enzymes helps protect the nervous system, and maintain a body that feels healthy and clear.
Receptor and Enzyme Activity Involved In CBG Benefits:
2. Gut Health
The inflammation reduction listed above helps treat stubborn IBS (irritable bowel syndrome) symptoms. COX1 is associated with adverse gut issues. CB2 activation is linked to anti-nausea and vomiting effects. Cannabigerol inhibits COX1 and is a CB2 agonist, explaining these effects.
Creating CB2 receptor activity is a suggested therapy for the treatment of acute, chronic, inflammatory and neuropathic pain. Alpha-2 adrenergic receptor agonists are also powerful tools for pain management. CBG, as a CB2 receptor agonist and an alpha-2 adrenergic receptor agonist, is intimately connected to analgesia.
4. Mood Elevation
CB1 receptor antagonism, or inhibition of CB1 activity, is an essential factor in the management of stress, anxiety, and depression. CB1 antagonism can help regulate the production of 2-AG a cannabinoid that is produced by our own body. 2-AG assists in the activation of both CB1 and CB2 receptors, helping to strike that critical balance between activity and inhibition. CB2 agonism also helps to reduce anxiety and depression. Cannabigerol acts as a vital CB1 inhibitor, and CB2 activator, leading to these biochemical responses.
Alpha-2 adrenergic receptor agonist therapies also help to treat anxiety, depression, neurosis, and addiction. Treating inflammation is also a great way to approach mood disorders, and in fact, inflammation reduction can help heal chronic depression. This makes CBG a valuable tool in mood therapy as its relevant activity is not limited to the endocannabinoid system.
5HT1a antagonism has been shown to boost memory and learning. CB2 activity also carries neuroprotective benefits. COX1/2 enzymes have neurotoxic effects, which is alleviated when they are inhibited. Alpha-2 adrenergic receptor agonists can promote neuroprotection. CBG implements all of these relevant activities and inhibitions.
Premier CBG For Sale
Until recently, there was not an efficient way to consume CBG. Cannabis plants typically only produce under 10% CBG when compared to their total cannabinoid content. Now, through selective breeding, we have created CBG cannabis strains that have over 90% cannabigerol! With these advancements, as well as the awareness of optimal CBD harvesting time, distributors can obtain pure and impactful CBG extracts.
Our CBG for sale at CBD Guru uses cutting edge cultivation and extraction techniques to provide you with the potency and purity you desire. The third-party lab-testing we provide guarantees the therapeutic benefits of our products. Just ask our many satisfied customers! Check out our shop, enjoy our educational articles, and feel free to reach out to our customer service team! We love connecting with our clients and helping guide them in their selection of the perfect hemp product.